NMDP HLA Frequencies by Race (US 2020 Census Adjusted)

This dataset contains HLA allele frequencies adjusted based on the 2020 US Census data. It provides information on allele frequencies across different racial groups as defined by the National Marrow Donor Program (NMDP).

Usage

nmdp_hla_frequencies_by_race_us_2020_census_adjusted

Format

A data frame with the following columns:

region

Geographical region associated with the data.

loci

HLA loci (e.g., A, B, C, DRB1).

allele

HLA allele name.

is_g

Indicator if the allele is a G group (logical).

nmdp_race_code

Race code as defined by the NMDP.

nmdp_af

Allele frequency as reported by the NMDP.

nmdp_calc_gf

Genotype frequency calculated by the NMDP.

us_2020_percent_pop

Percentage of the US population in 2020 for the given race.

us_2020_nmdp_gf

Genotype frequency adjusted for the 2020 US Census population.

Source

National Marrow Donor Program (NMDP) and US Census 2020 data. and nmdp_hla_frequencies_us_2020_census_adjusted.R

Details

This dataset is useful for analyzing HLA allele distributions and their representation across different racial groups in the US, adjusted for the 2020 Census population data. It can be used in studies related to population genetics, transplantation, and donor matching.